Alnylam Pharmaceuticals

    Medical Affairs Manager, TTR Cardiomyopathy - Germany

    Alnylam Pharmaceuticals
    Posted 11/11/2025Senior Level
    Full-time
    Healthcare
    Medical Affairs
    Cardiology
    Scientific Expertise
    KOL Engagement
    Medical Education

    Job Description

    Support cross-functional launch readiness and critical business operations post-launch activities. Develop and continuously maintain the highest scientific and medical expertise within TTR Cardiomyopathy (CM) and be acknowledged internally and externally as an expert in this area, developing peer-to-peer scientific relationships with HCPs and giving medical support to the corresponding cross-functional disease area teams. Collaborate with the Medical Affairs Manager for TTR Polyneuropathy to develop and implement a comprehensive Country Medical Affairs Plan and Strategy to support disease awareness, best clinical practice, and the overall corporate objectives. Identify key opinion leaders and cultivate a network of experts for TTR CM. Initiate and support high-impact medical education activities, including congress symposia, hospital or healthcare professional educational meetings, as well as provide medical and scientific input into the planning and execution of advisory boards. Actively engage with International and Global Medical Affairs and other functions, providing medical leadership within TTR CM to ensure effective local implementation of Alnylam's strategy and appropriate use of local market intelligence and development opportunities. Collaborate with patient advocacy groups. Manage requests for Alnylam product supply in off-label and compassionate use cases, in accordance with local laws and Alnylam procedures. Coordinate the timely and appropriate response to Medical Information inquiries, utilizing global medical information resources and ensuring compliance with local regulatory requirements. Support internal stakeholders in the Market Access process, including AMNOG. Train internal team members in relevant therapy areas and provide product training. MD (Medical Doctor) and/or PhD and/or equivalently academically qualified healthcare professional. A degree in medical or natural science (PhD, MD) is preferred. Previous experience in the field of cardiology in the German market strongly preferred. Proven basic science and/or clinical background enabling meaningful scientific engagement with healthcare professionals. Strong analytical skills as applied to medical, scientific, and technical information, with the ability to simplify scientific complexity. Experience in clinical research and investigator-sponsored trials. Experience in medical education and KOL engagement programs. Effective communication skills for evidence-based scientific exchange. Knowledge of drug development, GCP, and local regulations. Ability to work collaboratively and cross-functionally. Strong management, planning, decision-making, and accountability skills. Confidence and professional competence to gain respect and credibility at all levels within and outside the company, with the capability to represent the company externally. Fluent in German and English, both written and verbal. Willingness to travel 50-60% of the time.

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